The CareNow is located in the 300 block of Main Street. Patients are currently being held inside the clinic as crews at the scene examine staff and others inside the building.
"The patient claims to have had contact with the Dallas 'patient zero,'" according to a statement from Dana Baird-Hanks, a spokeswoman with the city of Frisco. The first patient diagnosed with Ebola in Dallas died Wednesday.
According to a statement from the clinic, the patient answered "yes" on a form "regarding travel to West Africa."
Police and fire units have surrounded the facility, taped off a gray SUV and isolated other patients at the facility.
Outside the building, people in hazardous material suits readied an ambulance for transport of the patient.
Officials say a conference will be held at 3:30 p.m.
